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Inhalation: Harmful if swallowed. Linking to a non-federal website does not constitute an endorsement by CDC or any of its employees of the sponsors or the information and products presented on the website. May cause allergic skin and respiratory reaction. SAFETY DATA SHEET (in accordance with Regulation (EU) 2015/830) 108120-Maleic anhydride Version: 3 Revision date: 19/04/2016 Page 2 of 9 Print date: 19/04/2016 -Continued on next page.- P304+P340 IF INHALED: Remove person to fresh air and keep comfortable for breathing. Wash out mouth with water. 5. Causes eye burns. Appearance: white lumps. A poison by intravenous route. Skin: Exposure to maleic anhydride may occur from accidental releases to the environment or in workplaces where it is produced or used. Memorandum. May cause blistering of the skin. Show this safety data sheet to the doctor in attendance.Move out of dangerous area. Polynt Group produces a great variety of anhydrides, but the most important ones are: Phthalic Anhydrides, Maleic Anhydride, Trimellitic Anhydride Repeated Pesticide properties for Maleic hydrazide, including approvals, environmental fate, eco-toxicity and human health issues Ingestion: Up to 10 mg/m3: (APF = 25) Any supplied-air respirator operated in a continuous-flow mode£(APF = 50) Any self-contained breathing apparatus with a full facepiece(APF = 50) Any supplied-air respirator with a full facepiece, Emergency or planned entry into unknown concentrations or IDLH conditions: (APF = 10,000) Any self-contained breathing apparatus that has a full facepiece and is operated in a pressure-demand or other positive-pressure mode(APF = 10,000) Any supplied-air respirator that has a full facepiece and is operated in a pressure-demand or other positive-pressure mode in combination with an auxiliary self-contained positive-pressure breathing apparatus, Escape: (APF = 50) Any air-purifying, full-facepiece respirator (gas mask) with a chin-style, front- or back-mounted organic vapor canister having an N100, R100, or P100 filter. Click here for information on selection of N, R, or P filters.Any appropriate escape-type, self-contained breathing apparatus, Important additional information about respirator selection, cis-Butenedioic anhydride, 2,5-Furanedione, Maleic acid anhydride, Toxilic anhydride. Maleic Anhydride Flinn Scientific, Inc. P.O. double vision, and "halo" vision. Safety Data Sheet 24 hour Emergency Response No. The anhydride of maleic acid has five atoms in its cyclic molecule, the unsaturated bond undergoes free radical polymerization in the presence of an initiator. Recrystallize the maleic anhydride from toluene. Causes redness and pain. : 108-31-6 Molecular Weight: 98.06 Chemical Formula: C4H2O3 Company: ADDTEK CHEMICAL SHANGHAI CO LTD TEL: +86 21 63352916 FAX: +86 21 51010033EXT8839 Product name : Maleic anhydride Product Number : 63200 Brand : Sigma-Aldrich Index-No. Danger! (2) Maleic anhydride has an acrid odor, with an odor threshold of 0.32 parts per million (ppm). 1272/2008, Regulation (EC) No.1907/2006 Maleic Anhydride, rev 2 7/2012 Page 2 Basis for Classification This substance is classified based on Directive 1272/2008/EC and its amendments (CLP Regulation,GHS) MALEIC ANHYDRIDE (108-31-6) Product Identification Synonyms: cis-Butenedioic anhydride; 2,5-furandione; toxilic anhydride CAS No. Hazard classification & labelling Hazard classification and labelling. NCI [1974]. May cause conjunctivitis. FIRST AID MEASURES General advice Consult a physician. Exposure to high fume concentrations cause photophobia, Combustible Solid, but may be difficult to ignite. MALEIC ACID page 2 of 6 This Fact Sheet is a summary source of information of all ... (as Maleic Anhydride) exists, use a MSHA/NIOSH approved self-contained breathing apparatus with a full facepiece operated in a … tract irritation and possible burns. Corrosive. May cause digestive tract Risk Statements: 36/37/38 R36/37/38:Irritating to eyes, respiratory system and skin. Maleic anhydride released into water will hydrolyze rapidly (half-life 0.37 min) to maleic acid. Colorless needles, white lumps, or pellets with an irritating, choking odor. : 607-096-00-9 CAS-No. If not breathing, give artificial respiration. Do NOT induce vomiting. Causes chemical burns to the respiratory tract. Maleic Anhydride Safety Data Sheet International Diol Company SAFETY DATA SHEET according to Regulation (EC) No. cis-Butenedioic anhydride, 2,5-Furanedione, Maleic acid anhydride, Toxilic anhydride Colorless needles, white lumps, or pellets with an irritating, choking odor. When heated to decomposition it emits acrid smoke and irritating vapors. Causes severe eye and skin irritation with possible The Centers for Disease Control and Prevention (CDC) cannot attest to the accuracy of a non-federal website. Dissolve the residue in a minimal amount of chloroform. Wear safety goggles or eye protection in combination with breathing protection if powder. Inhalation of high concentrations may cause pulmonary edema. Histological examination revealed nephrosis which increased in severity with the dose above 100 mg/kg. Personal Protective Equipment Eyes: Wear appropriate protective eyeglasses or chemical safety goggles as described by OSHA's eye and face protection regulations in … Eye: ], inhalation, ingestion, skin and/or eye contact, irritation nose, upper respiratory system; conjunctivitis; photophobia (abnormal visual intolerance to light), double vision; bronchial asthma; dermatitis, Centers for Disease Control and Prevention. pain. exposure may cause allergic respiratory reaction (asthma). Environmental: Maleic anhydride's fate in soil is unknown. Maleic anhydride undergoes a potentially explosive exothermic Diels-Alder reaction with 1-methylsilacyclopenta-2,4-diene at 150C [Barton, T. J., J. Organomet. Move out of dangerous area. Strong oxidizers, water, alkalis, metals, caustics & amines above 150°F Maleic acid 110-16-7 >95 4. respiratory tract. Substance Any concentration shown as a range is to protect confidentiality or is due to batch variation. Eye Contact Rinse immediately with plenty of water, also under the eyelids, for at least 15 minutes. "Maleic Anhydride, Maleic Acid, and Fumaric Acid." Rinse mouth with water (only if the person is conscious). Stir the mixture for 10 min. irritation with nausea, vomiting, and diarrhea. Harmful if swallowed. Since it biodegrades in sewage treatment plants and hydrolyzes, it's likely that it will degrade in soil. Box 219, Batavia, IL 60510 (800) 452-1261 Chemtrec Emergency Phone Number: (800) 424-9974 Safety Statements :26-36/37/39 System RfD (mg/kg-day) Basis PoD Composite UF Confidence; Urinary: 1 x 10 -1: Renal lesions: NOAEL : 1.0 x 10 1 mg/kg-day 108 -31 -6 203 -571 -6 607 -096 -00 -9 - 4. MATERIAL SAFETY DATA SHEET MALEIC ANHYDRIDE 1. First-aid measures General Advice Show this safety data sheet to the doctor in attendance. 1.3 Details of the supplier of the safety data sheet Company : Central Drug House (P) Ltd 7/28 Vardaan House New Delhi-10002 INDIA Target Organs: Lungs, respiratory system, eyes, Since it biodegrades in sewage treatment plants and hydrolyzes, it's likely that it will degrade in soil. (5,8) The vapor pressure for maleic anhydride is 0.1 to 0.2 mm Hg at 25 °C. Causes respiratory burns. First Aid Measures Description of Firstaid Measures General Advice: Consult a physician. If inhaled If breathed in, move person into fresh air. Immediate medical attention is required. Remove victim to fresh Chemical name :maleic anhydride Substance/mixture : Occupational exposure limits, if available, are listed in Section 8. Product name : Maleic Anhydride CAS-No. 6. P342+P311 If experiencing respiratory symptoms: Call a POISON CENTER/doctor. Prolonged or repeated skin contact may cause dermatitis. Potential Health Effects Show this safety data sheet to the doctor in attendance. Chemical safety data sheet sd-88: properties and essential information for safe handling and use of maleic anhydride. Product Safety Assessment: Maleic Anhydride Last Revised: August 2015 Page 2 of 3 Potential Human Health Effects Occupational Exposure Potential for occupational exposure to Maleic Anhydride exists during manufacture, at transloading, storage and staging areas, and during mixing and sampling operations in the manufacture of other products. : 108-31-6 1.2 Relevant identified uses of the substance or mixture and uses advised against Identified uses : Laboratorychemicals, Industrial & for professional use only. Causes redness and Maleic anhydride is a colorless to white solid that forms orthorhombic crystals and decomposes in water. OSHA Vacated PELs: Acetic anhydride: No OSHA Vacated PELs are listed for this chemical. Saving Lives, Protecting People, The National Institute for Occupational Safety and Health (NIOSH), National Institute for Occupational Safety and Health, A – NIOSH Potential Occupational Carcinogens, E – OSHA Respirator Requirements for Selected Chemicals, G – 1989 Air Contaminants Update Project: Exposure Limits NOT in Effect, Type C & CE – Definitions for Type C and Type CE Respirators, U.S. Department of Health & Human Services. For safe handling and use of maleic anhydride 's fate in soil will hydrolyze (... Can not attest to the doctor in attendance the accuracy of a non-federal website subject to the of... In sewage treatment plants and hydrolyzes, it 's likely that it will degrade in soil difficult to ignite a! Skin sensitization, an allergic reaction, which becomes evident upon re-exposure to material. 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